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Monday, July 28, 2025

From Seed to Survival: Growing Podophyllum hexandrum in Kashmir’s Climate

Podophyllum hexandrum, also known as the Himalayan May Apple, is a medicinal plant with a variety of uses, primarily in traditional medicine. It is known for its anticancer properties, particularly due to the presence of podophyllotoxin, which is used in the synthesis of anti-cancer drugs like etoposide and teniposide. Additionally, it has been traditionally used to treat skin diseases, digestive issues, and as a purgative and laxative. 
Podophyllum hexandrum in Kashmir

Specific Uses:
Anticancer : Podophyllotoxin, found in the rhizomes, is a key ingredient in the synthesis of drugs like etoposide and teniposide, which are used in the treatment of various cancers including lung cancer, leukemia, and other solid tumors. 

Skin Diseases : The crushed leaves and roots are used to treat skin diseases, rashes, and eczema. 

Digestive Issues : Ripe fruit juice is traditionally used for stomach ulcers and dyspepsia, and the fruit itself is eaten raw for chest congestion and gastric problems. 

Purgative and Laxative : The rhizome powder is used as a purgative and laxative, and the resin is used in veterinary medicine as a cathartic for dogs. 

Traditional Medicine : In various regions, it is used to treat a wide range of ailments including colds, constipation, septic wounds, burning sensations, erysipelas, mental disorders, plague, allergic and inflammatory skin conditions, and even some forms of cancer. 

Other : The pericarp of the mature red fruit is used to treat eye wounds in cattle.